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1 Ann Intern Med, Feb 1994; 120: 227-237
2 Circulation. 1995;92:320-326
3 News Hour with Jim Lehrer (PBS); 10-12-1998
4 Circulation. 1998;97:363-368
5 Book;Vitamin C The Future is Now; by Jeffery Bland, Ph.D
6 Circulation. 1998;98:2709-2715
7 Mol. Biol. Cell 2000 11: 1859-1874
8 Science 2003 299: 896-899

Based on breakthrough Nobel Prize winning science, Oxegen AKG Nitric Oxide Stimulator helps to increase blood flow and ease circulation throughout the body by stimulating the natural production of Nitric Oxide (NO), resulting in vasodilation (the widening of blood vessels).*

What is Nitric Oxide?
Nitric Oxide is a simple molecule consisting of two atoms, nitrogen and oxygen, produced by a process known as Nitric Oxide Synthase (NOS) – a gas made by our blood vessels that causes vasodilation (blood vessel relaxation and widening) for greater flow of blood, nutrients, amino acids and oxygen delivery throughout the body and into the cells.*1

What is Oxegen AKG?
Oxegen AKG is a target specific nutraceutical supplement, scientifically formulated with reaL-AKG™ Matraxol Technology to perform a single targeted task – to help stimulate the production of Nitric Oxide, encouraging vasodilation for greater blood, nutrient and oxygen flow throughout the body and into the cells.*1

What is reaL-AKG™ Matraxol Technology?
The reaL-AKG Matraxol Technology in Oxegen AKG forms a complex containing L-Arginine, Glutamate, Succinyl, Coenzyme A and other nutrients that are bound in a neutral ionic state to form a complex that mimics the same processes your body naturally uses to supply Arginine in its final form – L-Arginine Alpha-Ketoglutarate (AKG), a branched chain amino acid compound – as a catalyst to activate the enzyme Endothelial Nitric Oxide Synthase (eNOS) that triggers Nitric Oxide production, encouraging vasodilation (blood vessel widening) for greater blood, nutrient and oxygen flow throughout the body and into the cells.*1,2

Standard Arginine or other AKG products, if not bound in a neutral ionic state, when ingested will search for other elements to bind with, resulting in either the Nitric Oxide triggering nutrients being hijacked by another bodily function, or worse, the creation of harmful, Nitric Oxide inhibiting free-radicals – which is the reason little (if any) benefit is often realized by taking standard Arginine or other AKG supplementation products.*1,2,6

Only Oxegen AKG utilizes reaL-AKG Matraxol Technology that is bound in a neutral ionic state, preventing the generation of harmful, Nitric Oxide inhibiting free-radicals that render a superior form of Arginine Alpha Ketoglutarate (AKG), resulting in a highly bio-absorbable and bio-available delivered form of L-Arginine with a single target-specific task – the production of beneficial Nitric Oxide for improved circulation, blood, nutrient and oxygen flow.*1,2,6

Why is Oxegen AKG Known as a Target-Specific Metabolic Integrator?
Oxegen AKG utilizes reaL-AKG Matraxol Technology to mimic the same processes your body uses to supply Arginine in its final form – L-Arginine Alpha-Ketoglutarate – as a catalyst to induce Endothelial Nitric Oxide Synthase (eNOS) to encourage Nitric Oxide production, and subsequently, vasodilation for greater blood, nutrient and oxygen flow throughout the body.*1

What Specifically is the "AKG" in Oxegen AKG?
L-Arginine Alpha-Ketoglutarate (AKG) is a branched chain amino acid compound discovered in the 1980s. L-Arginine, along with Glutamate, Glutamine and Proline, are members of the Glutamate family of amino acids. The amino acid chain comprises AKG, which is a combination of the amino acids L-Arginine, Glutamine and OKG (which is Ornithine alpha-Ketoglutarate), or a combination of the amino acids Ornithine and Glutamine. Ornithine and Alpha-Ketoglutarate can be branched together because they are both precursors to Glutamine and L-Arginine within the body. The reaL-AKG Matraxol Technology in Oxegen AKG provides a superior form of L-Arginine that is constructed to deliver L-Arginine throughout the body and into the cells to specifically initiate the release of Nitric Oxide. The reaL-AKG Matraxol Technology renders a highly bio-absorbable and bio-available form of L-Arginine for optimum cellular utilization.*

Can I Just Take Standard L-Arginine to Boost Nitric Oxide?
The reaL-AKG Matraxol Technology in Oxegen AKG form a complex containing L-Arginine, Glutamate, Succinyl, Coenzyme A and other nutrients. Unlike standard Arginine that is sometimes taken to improve Nitric Oxide production, only Oxegen AKG utilizes reaL-AKG Matraxol Technology that is bound in a neutral ionic state, resulting in a superior form of Arginine Alpha Ketoglutarate (AKG).*

Arginine, if not bound in a neutral ionic state, when ingested will search for other elements to bind with, resulting in either its benefit being hijacked by another bodily function, or worse, the creation of harmful, Nitric Oxide inhibiting free-radicals – which is the reason little (if any) benefit is often realized by taking standard Arginine supplementation. Since Oxegen AKG is bound in a neutral ionic state (thus, preventing it from incorrectly binding with other elements), its function is targeted to one task – the creation of beneficial Nitric Oxide for greater blood flow, encouraging improved delivery of oxygen and nutrients throughout the body and into the cells.*

Does Oxegen AKG Actually Make Nitric Oxide?
No. Oxegen AKG's reaL-AKG Matraxol Technology mimics the biomolecular and physiological reactions your body naturally goes through during the L-Arginine/Nitric Oxide conversion process, resulting in a single target-specific formula with just one task – producing Nitric Oxide. However, before Nitric Oxide production can occur, the nutrient complex in Oxegen AKG must arrive in the small intestine intact. Oxegen AKG's patent-pending SurSorb Sustained Release Technology (SRT) helps ensure the Oxegen AKG complex arrives intact.*

How Does SurSorb™ (SRT) Ensure Absorption?
Oxegen AKG utilizes SurSorb Sustained Release Technology (SRT) to ensure Oxegen AKG's reaL-AKG Matraxol complex survives the harsh acidic environment of the stomach and is not broken down during transition through the stomach to the small intestine – instead, arriving ready for absorption via the millions of finger-like intestinal villi.*

For simplicity, think of the intestinal villi as being "coded" (like a lock), absorbing only certain nutrients (which hold the key). Without the correct key, the nutrient will not be accepted for absorption from the intestinal villi to the blood stream. Oxegen AKG's reaL-AKG Matraxol Technology works to bond with a specific transfer enzyme that unlocks the villi key (allowing absorption) – triggering endothelial derived Nitric Oxide Synthase (eNOS), the enzyme responsible for stimulating the natural production of Nitric Oxide. As Nitric Oxide levels increase, nitro vasodilation (blood vessel widening) occurs, increasing blood flow and the delivery of nutrients, amino acids and oxygen into the cells.*

How Does Oxegen AKG Affect Muscle for Athletes & Body Builders?
Research has shown Nitric Oxide mediates muscle satellite cell activation – the precursors that enable muscle repair and adaptation – with one study concluding, "...[Nitric Oxide] holds a tantalizing potential to prevent or treat muscle atrophy and to promote hypertrophy and new fiber growth (...as in athletic training...) in otherwise healthy muscle." *7

Oxegen AKG is formulated to help generate an everlasting PUMP through mediation of the cell-signaling molecule Nitric Oxide to help amplify growth signals, accelerate fast and slow twitch muscle fibers and provide complete full-body recovery and increased Endurance Index to help muscles grow. Oxegen AKG with reaL-AKG Matraxol Technology is a must try for athletes and bodybuilders alike!*

Is Oxegen AKG Scientifically Proven?
The breakthrough science behind the nitro vasodilator effect of Oxegen AKG is based on both the Nobel Prize Winning Science in Medicine for Nitric Oxide's role in mediating blood flow and the Human Genome Project's identification of the physiological mechanism utilized to initiate Nitric Oxide synthesis.*

The nitro vasodilator benefits of Nitric Oxide have been demonstrated in controlled clinical trials, with one such trial concluding the contribution of Nitric Oxide to metabolic coronary vasodilation in the human heart resulting in both a (i) 50% increase in blood flow and (ii) 68% reduction in coronary vascular resistance.*2

Additionally, a secondary benefit of Nitric Oxide is its ability to act as its own self-defense mechanism, lubricating the endothelial lining of blood vessels, like Teflon – keeping foreign particles from sticking to blood vessel walls.*3

Why Can’t I Take Oxegen AKG if I Have Cold Sores?
Many people with cold sores are often concurrently taking Lysine. Arginine will bind with Lysine, rendering the Lysine ineffective and requiring a higher dosage of Lysine, which may not be beneficial.*

Will Oxegen AKG Interfere with Blood Pressure Medication?
While Oxegen AKG will not interfere with the medication itself, the blood vessel widening mechanism of Oxegen AKG's reaL-AKG Matraxol Technology may lower blood pressure – resulting in exceedingly low, unhealthy blood pressure levels if combined with blood pressure medication.*

Can I take Oxegen AKG if I'm currently Taking Thyroid Medication?
No. As both thyroid medications and Oxegen AKG's reaL-AKG Matraxol Technology can affect blood pressure, resulting in unhealthy blood pressure levels. Combining the use of Oxegen AKG with thyroid medication is not recommended.*

Can I take Oxegen AKG with Sildenafil Citrate or Other Sexual Medications?
No. Sildenafil Citrate or other sexual medications and Oxegen AKG's reaL-AKG Matraxol Technology can affect blood pressure, resulting in unhealthy blood pressure levels. Combining the use of Oxegen AKG with Sildenafil Citrate or other sexual medications is not recommended.*

Can I take Oxegen AKG with DHEA?
No. As both DHEA and Oxegen AKG's reaL-AKG Matraxol Technology can affect blood pressure, resulting in unhealthy blood pressure levels. Combining the use of Oxegen AKG with DHEA is not recommended.*

How Does Oxegen AKG Provide Energy without Stimulants?
Studies have shown the mechanism in Oxegen AKG can help increase blood flow. Thus, as circulation is improved with Oxegen AKG, so too are the nutrients, amino acids and oxygen delivered throughout the body and into the cells – helping to fuel metabolism and energy gains.*

How Does Oxegen AKG Burn Fat?
The Mitochondria provide the energy that a cell needs to move, divide and contract – but more importantly, it is where sugar is combined with oxygen and where both dietary and stored fat is burned. Thus, with more Mitochondria present, more fat can be burned. The reaL-AKG Matraxol Technology in Oxegen AKG helps to increase Nitric Oxide levels, which in turn help increase the number of Mitochondria, allowing greater fat burning to occur.*8

Why Do I Have to Take Oxegen AKG on an Empty Stomach?
It is preferable to take Oxegen AKG on an empty stomach due to the limited absorption sights that take the Oxegen AKG formula from the small intestine into the bloodstream.*

How Long Do I Have to Take Oxegen AKG Before I Can Feel Results?
You may notice a subtle difference noticed within the first 4 hours of taking Oxegen AKG – but of course, everyone’s metabolism is different, therefore more visible and dramatic results can range from 4 to 12 days.*

How Does Oxegen AKG Work to Enhance Sexual Performance & Sensitivity?
Oxegen AKG's reaL-AKG Matraxol Technology helps to boost sexual function, feeling and desire by stimulating the production of Nitric Oxide for optimum blood flow and circulation – encouraging healthy sexual function in men and increased sensitivity in women.*1

Is Oxegen AKG Affected by Caffeine, Nicotine or Other Stimulants?
Most stimulants, such as caffeine, nicotine (to a lesser extent), ephedrine and synephrine constrict blood vessels – lessening the benefits of the Oxegen AKG's reaL-AKG Matraxol Technology.*

Why Does Oxegen AKG Contain Vitamin C?
Studies have also shown Nitric Oxide production can become impaired by the presence of oxygen free radicals, resulting in oxidative stress – inactivating or degrading intracellular availability of L-Arginine (the precursor of Nitric Oxide Synthase). For this reason, Oxegen AKG is formulated with Vitamin C (as calcium ascorbate) to deliver both sustained delivery of powerful antioxidants and greater bio-availability, while ensuring less stomach upset for individuals sensitive to Vitamin C.*4,5

Who Should Try Oxegen AKG?
Anyone who is not at risk and concerned with blood flow, lean muscle, oxidized fat burning, endurance, stamina, energy, sexual performance and enhanced low-carb dieting and exercise.* (Please see Warnings below for those who should not take Oxegen AKG).

What is the Correct Dosage for Oxegen AKG?
Oxegen AKG must be taken on an empty stomach either a half-hour before meals or an hour or more after eating, in accordance with the dosage chart. For best results, it is recommended to drink eight (8 oz.) glasses of water daily. Do not consume foods for at least 30 minutes before, or 30 minutes after, taking Oxegen AKG. Do not take servings after 3:00pm. Although Oxegen AKG contains no stimulants, it may keep you awake.*

For Athletes: If you are weight training or exercise frequently for sport or competition, drink at least eight (8 oz.) glasses of water on the days you don't train and ten to twelve (8 oz.) glasses on the days you do train. It is important to maintain your complex carbohydrate intake above 40% of your total daily caloric intake.*

Oxegen AKG utilizes reaL-AKG Matraxol and SurSorb Sustained-Release technologies to help ensure its increased effectiveness – enabling you to take only the minimum dosage to realize the maximum benefits. When you first start using Oxegen AKG, begin with the MINIMUM recommended dosage from the dosage chart. After 7 days of continuous use, you may increase to the maximum recommended dosage. Oxegen AKG must be taken on an empty stomach, either a half-hour before meals or an hour or more after eating.*

What's the Difference Between Oxegen AKG and Similar Products?
Don't be fooled by other formulas that may claim to contain the same ingredients as Oxegen AKG. Only Oxegen AKG utilizes reaL-AKG Matraxol and SurSorb™ Sustained Release Technology (SRT) that allow Oxegen AKG to deliver greater bio-absorption and bio-availability. Coupled with the utilization of higher quality, standardized ingredient compounds, Oxegen AKG requires a significantly smaller dosage to achieve – so you take far fewer tablets to achieve superior efficacy, resulting in much greater value!

Does Oxegen AKG Contain Artificial Binders or Fillers?
Oxegen AKG is allergen free of yeast, corn, soy, wheat, sugar or other sweeteners, artificial flavors, colors or preservatives and is manufactured to GMP standards. Store at controlled room temperature between 59°F and 86°F to maintain freshness. Do not refrigerate. This product utilizes Tamper-Evident packaging. Do not use if safety seal around bottle cap or printed inner seal is missing or broken.

Are there Consumer Warnings for Oxegen AKG?
Yes: Keep Out of the Reach of Children. Do not take if you are under 18 years of age. Do not use if you are pregnant or nursing, if you are at risk of or are being treated for diabetes or low blood pressure. Consult your healthcare professional before use if you are being treated for high blood pressure, diabetes, liver, thyroid, psychiatric disease or taking sildenafil citrate. Use this product with caution if you have renal or hepatic failure or have a history of cold sores. Caffeine or ephedrine based products may reduce the effectiveness. Do not use with products that contain Ephedra, as they may act as a vasoconstrictor, reducing benefit. Do not take your dosage after 3:00pm. Although this supplement contains no stimulants, it may keep you awake. High doses of arginine may be toxic and overuse may cause diarrhea, nausea, headache or allergic reaction.

Is Oxegen AKG Guaranteed?
Oxegen AKG is manufactured with only the highest quality ingredients to exacting standards and specifications, ensuring maximum potency, standardization and efficacy in every serving. We are confident in the quality of Oxegen AKG and guarantee every bottle!

Benefits & Advantages...

Helps Support Optimum Circulation & Blood Flow by encouraging the widening of blood vessels throughout the body. The nitro vasodilator benefits of Nitric Oxide have demonstrated a (i) 50% increase in blood flow and (ii) 68% reduction in coronary vascular resistance.*2

Helps Facilitate Lean Muscle Mass Production & Oxidized Fat Burning by helping to unlock the keys to a trimmer, leaner, stronger you through greater delivery of: amino acids (which build muscle), glucose (which provides energy), creatine (which fuels strength), and oxygen (for endurance).*7

Helps Speed Recovery from Physical Exertion by helping to increase blood flow and nutrients throughout the body and into the cells. Research has shown that a significant increase in exercise capacity is associated with healthy endothelial function.*6

Helps Boost Physical Endurance and Stamina by assisting oxygen and nutrient flow to muscle cells, stimulating muscle fiber growth and increasing endurance and stamina to help you get stronger and last longer with less fatigue – with research showing a significant increase in exercise capacity with healthy endothelial function.*6

Helps Enhance Intimate Performance in Men & Women by working to combat age-related and environmental factors that can decrease Nitric Oxide production. Oxegen AKG helps to boost sexual function, feeling and desire by stimulating the production of Nitric Oxide for optimum blood flow and circulation – encouraging healthy sexual function in men and increased sensitivity in women.*1

OXEGEN AKG (NEW) Patented real-AKG MATRAXOL Technology