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Fastin Pharmaceutical Grade Dietary Supplement FREE Shipping! |
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What is Fastin? Fastin Novel Stimulant Formulation Fastin is a pharmaceutical-grade dietary supplement indicated for weight loss in extremely overweight individuals. Fastin has both immediate and delayed release profiles for appetite suppression, energy, and weight loss. Fastin is comprised of nine pharmaceutical-grade fat loss catalysts at precise ratios in order to achieve its extraordinary results. Fastin's proprietary formula includes the following: R-Beta-methylphenylethylamine HCL - this amazing compound is the active isomer of MPEA much like 1R, 25 Norephedrine was of PPA years ago. This compound stimulates norepinephrin unlike any other and leads to appetite suppression, energy, and ultimately fat loss. Methylphenylethylamine tartrate - this is the racemic version of MPEA bound to tartaric acid, which keeps the molecule stable. This compound is found in Hi-Tech's line and is a rising star of the fat loss industry. N-methyl-phenylethylamine - is another isolated amine from Acacia rigidula that is both for stimulating fat burning and energizing effects. This is the N-methyl derivative of the compound, B-Phenylethylamine. This is a very potent compound for all who lack a chemistry degree. Methylsynephrine -is phenolic B-Phenylethylamine found in Acacia rigidula and some cacti, which produces considerable central nervous stimulation (CNS). With Hi-Tech's research over the past five years on Acacia rigidula (as Thermo-Rx®), Hi-Tech has identified and isolated severarl key phenylethylamine alkaloids. The newest of which is methylsynephrine. The alkaloids from' Acacia rigidula are biologically and physiologically similar to those found in ephedra, and possess properties that are shared with ephedra alkaloids. Scientifically, this is in part due to the similarities in pharmacokinetics and pharmacodynamics. The most obvious similarity is that Acacia alkaloids, like the ephedra alkaloids, readily pass into the brain. The main factor governing the transfer of small molecules into the central nervous system is lipophilicity. The distribution of drugs and/or compounds into the CNS from the blood is unique, because functional barriers are present that restrict entry of drugs into this critical site. One reason for this is that the brain capillary endothelial cells have continuous tight junctions; therefore, drug penetration into the brain depends on transcellular rather than paraceuliar transport between cells. The unique characteristics of pericapillary glial cells also contribute to the blood-brain barrier. At the choroids plexus, a similar blood-cerebrospinal fluid (CSF) barrier is present, except that it is epithelial cells that are joined by tight junctions rather than endothelial cells. As a result, the lipid solubility of the nonionized and unbound species of the drug is an important determinant of its uptake by the brain; the more lipophilic it is, the more likely it is to cross the blood-brain barrier. This situation is used in drugs design to alter the brain distribution, which is the case with drugs like amphetamine, phentermine, and benzphetamine. As you can see from the comparison of the structures of ephedrine, norephedrine, and methylsynephrine they all possess the N-methyl substituent of the aliphatic sidechain, which is characteristic of ephedrine and its congeners, as well as methylsynephrine, thus further increasing lipophilicity. What is a suitable substitute for ephedra? How about another beta agonist? Theobromine -is the primary methylxanthine found in products of the cocoa tree, Theobroma cocao. As a member of the methylxanthine family, it is thought to elevate levels of serotonin, the same action as the popular anti-depressants. Theobromine has a lot of research that shows its extraordinary effects on fat loss, appetite suppression, and mobilization of fatty deposits. Theobromine Phenylethylamine HCL -This amazing compound is probably the cleanest stimulant ever researched, and it is naturally present in human fluids and tissues. Although categorized as a stimulant, it has the remarkable ability to simulate the central nervous system without causing nervousness or the jittery feeling. Phenylethylamine is found in chocolate and is responsible for its effects on mood, appetite, and sense of well-being. Until recent discoveries, PEA, or phenylethylamine, was rapidly destroyed within the body. If included with novel delivery systems, phenylethylamine HCL is provided "safe transport" and this metabolic fate is avoided and pharmacological activity becomes extremely apparent. This catecholamine precursor is responsible for elevating the metabolic rate and promoting a sense of satiety. Phenylethylamine acts on alpha-receptors in the brain, as do norepinephrine and certain prescription anti-obesity drugs. It is also believed to cause the release of dopamine in the pleasure sensing areas of the brain. Phenylethylamine HCL has . a close chemical relationship to pharmaceutical stimulants, because it is the "backbone" of many pharmaceutical compounds. Yohimbine HCL -has been shown in many clinical trails to effectively block alpha 2 adrenoreceptors. These studies have found that yohimbine increases the amount of non-esterfied fatty acids (NEFA's) a product of lipolysis (the breakdown of fat), in the blood-stream for both lean and overweight subjects. There are a number of feedback mechanisms that prevent the release of norepinephrine (NE), one of the body's primary lipolytic hormones. When NE is released, such a when taking methylsynephrine and Acacia rigidula, it stimulates both the alpha and beta adrenoreceptors. Stimulation of the beta adrenoreceptors has the opposite effect, preventing the releas' of NE and lipolysis. Yohimbine prevents this negative feedback mechanism, and works in synergistic fashion with the other components to increase NE and lipolysis. There are a number of reasons why alpha-2 inhibition is specifically useful. First, while the beta-adrenergic system primarily controls lipolysis during periods of intense activity, during rest, which makes up most of our day, the alpha-adrenergic system is in control. Also, "stubborn fat" areas -usually the abdominal area in men and the glutofemoral area in women -contain a higher ratio of alpha-2 receptors making yohimbine particularly effective in these areas (whereas other drugs that increase NE ma' be somewhat counterproductive). Finally, alpha-2 blockade increases blood flow in adipose tissu which prevents fat from being retained in the area. Synephrine HCL - is a drug used primarily in fat loss, although the effectiveness is minimal in Fastin. It is very popular and has been used as an alternative to ephedrine (a substance with a history of controversy). Synephrine is derived primarily from the fruit of a small citrus tree. Caffeine Anhydrous USP - acts as a stimulant and thermogenic in humans, and is common! taken to boost energy or mental concentration. It will stimulate the central nervous system an the metabolism. Once metabolized, caffeine can increase lipolysis in the body. Caffeine may als increase the effectiveness of other substances such as ephedrine or yohimbe, and was incredibl popular in the commonly used ECA stack (ephedrine, caffeine, and aspirin). Fastin is definitely "Hot!" when it comes to weight loss supplements. Conclusion
For those of you looking for a truly effective weight loss supplement, there is a good rule of thumb that you can always follow when evaluating whether any weight loss product is "HoU" or "Not Hot!" What's "Not Hot!" in the weight loss supplement industry goes hand in hand with "too good to be true" and "quick and easy" hype-driven marketing. What's "Hot!" always goes hand in hand with substantiated, science-driven weight loss formulations. Do not take Fastin if you are allergic to other stimulants, or if you have:
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